In the U.S. during 2021, roughly 110,00 people died from causes that were 100% attributable to alcohol, like overdoses, car accidents, and alcoholic liver disease. On top of this, another 68,000 people died from causes that were partially attributable to alcohol, like cancer, heart disease, stroke, and organ failure. In sum, roughly 178,000 people died from excessive alcohol use. In comparison, roughly 109,000 people died from drug overdoses. However, this is likely an underestimate because drug overdoses have been undercounted in the past, and data on non-overdose drug deaths like car accidents and chronic diseases are unavailable. Lastly, 49,000 people died from gun suicides, homicides, and accidents.