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When scientists at the biotechnology firm Amgen attempted to confirm the findings of 53 peer-reviewed papers that presented the results of lab experiments related to cancer drugs, what portion of these studies were they able to confirm?

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In 2012, the journal Nature published a study by Amgen scientists who had attempted to confirm the findings of 53 prominent peer-reviewed papers that present results of lab experiments related to cancer drugs. The scientists were able to confirm 6% of these results, despite the fact that "when findings could not be reproduced, an attempt was made to contact the original authors, discuss the discrepant findings, exchange reagents and repeat experiments under the authors' direction, occasionally even in the laboratory of the original investigator." Although peer-reviewed research is considered to be the gold standard of scientific credibility, reams of facts about peer-reviewed publications and candid statements from people involved with them have exposed thousands of false or questionable findings in recent years.

Documentation2012 Nature PaperJunk Science




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